Environmental Toxicology

A fundamental concept of environmental toxicology is that all chemicals are poisons at a high enough dose. The concept of threshold dosages below which adverse effects will not occur is the keystone concept of all experimental toxicology. Toxicology is the study of the interaction between chemicals and living organisms and quantifying the dose levels at which adverse effects are observed. It considers the uptake of a chemical, the elimination of the chemical, and all the transport, storage, metabolism, and adverse effects that might occur prior to elimination. Knowledge of the potential adverse effects of specific chemicals can be crucial in establishing cause and effect relationships in assessment of occupational or environmental exposure cases.

"All things are toxic, the right dose differentiates a poison and a cure."

- Parcelsus, early 1500s

Cox-Colvin & Associates' environmental toxicologists have extensive knowledge and experience in evaluating and assessing the mechanistic and overall toxicological properties of chemicals under various occupational and environmental release scenarios. Our areas of expertise include the following:

  • Toxicity assessments for humans and various aquatic and terrestrial biota
     
  • Development and review of toxicity criteria
     
  • Bioavailability assessments
     
  • Biomonitoring and medical monitoring studies
     
  • Medical records reviews
     
  • Risk Communication
     
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